Protein name:
Multidrug resistance-associated protein 1 ;
Alternative:
Leukotriene C(4) transporter (LTC4 transporter) ;ATP-binding cassette sub-family C member 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MALSSFCSSD | GSDPLWDWNV | TWHTSNPDFT | KCFQNTVLTW | VPCFYLWSCF |
100:
PLYFLYLSRH | DRGYIQMTHL | NKAKTALGFF | LWIICWADLF | YSFWERSQGM |
150:
LLAPVLLVSP | TLLGITMLLA | TFLIQFERRK | GVQSSGIMLT | FWLVALLCAL |
200:
AILRSKIISA | LKKDAQVDMF | RDSAFYLYFT | LVFIQLVLSC | FSDSSPLFSE |
250:
TVRDPNPCPE | SSASFLSRIT | FWWITGMMVQ | GYRQPLKSSD | LWSLNKEDTS |
300:
EEVVPVLVNN | WKKECVKSRK | QPVRIVYAPP | KDPTKPKGSS | QLDVNEEVEA |
350:
LIVKSSHKDR | DPSLFKVLYK | TFGPYFLMSF | LYKALHDLMM | FAGPEILELI |
400:
INFVNDREAP | DWQGYLYTAL | LFVSACLQTL | ALHQYFHICF | VTGMRIKTAV |
450:
VGAVYRKALV | ITNSARKSST | VGEIVNLMSV | DAQRFMDLAT | YINMIWSAPL |
500:
QVTLALYFLW | LNLGPSVLAG | VAVMILMVPF | NAVMAMKTKT | YQVAHMKSKD |
550:
NRIKLMNEIL | NGIKVLKLYA | WELAFQDKVM | NIRQEELKVL | KKSAYLAAVG |
600:
TFTWVCTPFL | VALSTFAVFV | TVDEKNILDA | KKAFVSLALF | NILRFPLNIL |
650:
PMVISSIVQA | SVSLKRLRIF | LSHEELEPDS | IERWSIKDGG | GMNSITVKNA |
700:
TFTWARDEPP | TLNGITFAIP | DGALVAVVGQ | VGCGKSSLLS | ALLAEMDKVE |
750:
GHVTLKGSVA | YVPQQAWIQN | DSLRENILFG | RPLQEHCYKA | VMEACALLPD |
800:
LEILPSGDLT | EIGEKGVNLS | GGQKQRVSLA | RAVYCNSDIY | LLDDPLSAVD |
850:
AHVGKHIFEK | VVGPMGLLKN | KTRILVTHGI | SYLPQVDVII | VMSGGKISEM |
900:
GSYQELLDRD | GAFAEFVRTY | ANTEQDLASE | DDSKNGVSGL | GKESKPVENG |
950:
ILVTDAVGKP | LQRHLSNSSS | HSVVTNQQHS | STAELQKSGV | KEETWKLMEA |
1000:
DKAQTGQVKL | SVYWNYMKAI | GLCISFLSIF | LFLCNHVSAL | ASNYWLSLWT |
1050:
DDRPAVNGTQ | ENRNFRLSVY | GALGILQGVA | VFGYSMAVSI | GGIFASRRLH |
1100:
LDLLQNVLRS | PMSFFERTPS | GNLVNRFSKE | LDTVDSMIPQ | VIKMFMGSLF |
1150:
SVIGAVIIIL | LATPIAAVII | PPLGLVYFFV | QRFYVASSRQ | LKRLESVSRS |
1200:
PVYSHFNETL | LGVSVIRAFE | EQERFIRQSD | LKVDENQKAY | YPSIVANRWL |
1250:
AVRLECVGNC | IVLFAALFAV | ISRHSLSAGL | VGLSVSYSLQ | ITAYLNWLVR |
1300:
MSSEMETNIV | AVERLKEYSE | TEKEASWQIQ | ETAPPSTWPH | SGRVEFRDYC |
1350:
LRYREDLDLV | LKHINVTIEG | GEKVGIVGRT | GAGKSSLTLG | LFRINESAEG |
1400:
EIIIDGINIA | KIGLHNLRFK | ITIIPQDPVL | FSGSLRMNLD | PFSQYSDEEV |
1450:
WMALELAHLK | GFVSALPDKL | NHECAEGGEN | LSVGQRQLVC | LARALLRKTK |
1500:
ILVLDEATAA | VDLETDDLIQ | STIRTQFEDS | TVLTIAHRLN | TIMDYTRVIV |
1532:
LDKGEIRECG | APSELLQQRG | VFYSMAKDAG | LV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Mouse
Dog
Bovine
ELISA Kit for Rat Multidrug resistance-associated protein 1
ELISA Kit for Rat Multidrug resistance-associated protein 1
ELISA Kit for Rat Multidrug resistance-associated protein 1
ELISA Kit for Rat Multidrug resistance-associated protein 1
ELISA Kit for Rat Multidrug resistance-associated protein 1
ELISA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
CLIA Kit for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Polyclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Monoclonal Antibody for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
Protein for Rat Multidrug resistance-associated protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
Sprague-Dawley .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;MUTAGENESIS OF LEU-983; GLN-1090; SER-1101; VAL-1106 AND ALA-1243
strain :
Sprague-Dawley .
tissue :
Skeletal muscle .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
Sprague-Dawley .
tissue :
Spleen .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
Sprague-Dawley .
tissue :
Spleen .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 711-1532 (ISOFORM 1)
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1426-1532 (ISOFORMS 1/2)
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION